Methods and Compositions to Modulate RNA Processing

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United States of America Patent

APP PUB NO 20170044529A1
SERIAL NO

15166085

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Abstract

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The present disclosure provides methods and compositions to selectively modulate RNA processing. The methods and compositions selectively enhance or repress RNA processing by up- or down-regulating Drosha expression and/or by providing RNA sequences with mismatches introduced or removed 5 and/or 9-12 nucleotide positions from the Drosha cutting site. Therapeutic uses of the methods and compositions are also described.

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UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION4311 11TH AVENUE NE SUITE 500 SEATTLE WA 98105-4608

International Classification(s)

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  • 2016 Application Filing Year
  • C12N Class
  • 7780 Applications Filed
  • 4946 Patents Issued To-Date
  • 63.58 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances20162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Banik, Pratyusha Bothell, US 2 23
Beem, Alan Seattle, US 2 23
Ruohola-Baker, Hannele Seattle, US 10 10
Shannon, Sandra Sammamish, US 2 23
Sperber, Henrik Seattle, US 4 25

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  • 1 Citation Count
  • C12N Class
  • 53.39 % this patent is cited more than
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges2925224021854181131251101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0200400600800100012001400160018002000220024002600280030003200

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