Inhibitors of JMJD2C as Anticancer Agents

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United States of America Patent

APP PUB NO 20170044107A1
SERIAL NO

15306460

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure provides compounds, pharmaceutical compositions and related methods for the treatment of cancer, e.g., castration-resistant prostate cancer (CRPC). Specifically, the present disclosure provides a series of 8-hydroxyquinoline derivatives which show cytotoxic effects on androgen-independent prostate cancer cells.

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Patent Owner(s)

Patent OwnerAddress
THE J DAVID GLADSTONE INSTITUTES1650 OWENS STREET SAN FRANCISCO CA 94158

International Classification(s)

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  • 2015 Application Filing Year
  • C07D Class
  • 5466 Applications Filed
  • 4606 Patents Issued To-Date
  • 84.27 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances20152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ding, Sheng Orinda, US 111 927
Xie, Min Daly City, US 71 722

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  • C07D Class
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges158718941835528419501 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7081 - 90010020030040050060070080090010001100120013001400150016001700180019002000

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