Bioactive conjugates for oligonucleotide delivery

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United States of America Patent

PATENT NO 10633653
APP PUB NO 20170043024A1
SERIAL NO

15236051

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Abstract

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Provided herein are self-delivering oligonucleotides that are characterized by efficient RISC entry, minimum immune response and off-target effects, efficient cellular uptake without formulation, and efficient and specific tissue distribution.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF MASSACHUSETTSONE BEACON STREET 31ST FLOOR BOSTON MA 02108

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aronin, Neil Newtonville, US 47 753
Coles, Andrew Boston, US 12 135
Haraszti, Reka Boston, US 8 57
Hassler, Matthew Worcester, US 26 306
Khvorova, Anastasia Westborough, US 393 10160
Nikan, Mehran Boston, US 8 56
Osborn, Maire Boston, US 6 57
Turanov, Anton Boston, US 13 89

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