Compounds and use thereof in the expansion of hematopoietic stem cells and/or hematopoietic progenitor cells
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United States of America Patent
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May 12, 2020
Grant Date -
Feb 9, 2017
app pub date -
Apr 21, 2015
filing date -
Apr 22, 2014
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Abstract
Compounds of general formula or salts or prodrugs thereof, are provided and described herein. The compounds are useful to expand hematopoietic stem cell and/or hematopoietic progenitor cell populations. Particularly, the hematopoietic cells are human cells. The compounds are also useful in the medical treatment of hematopoietic disorder/malignancy, an autoimmune disease and/or an inherited immune-deficient disease in a subject.
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