PROGNOSTIC TESTS FOR HEPATIC DISORDERS

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United States of America Patent

SERIAL NO

15302708

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Abstract

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An in vitro prognostic method for assessing the risk of death or of liver-related event in a subject, includes: a) obtaining at least one, preferably 2, of the following variables from the subject: i. biomarkers measured in a sample from the subject; ii. clinical data; iii. binary markers; iv. blood test results; b) optionally obtaining at least one blood test result by univariate combination, preferably with a binary logistic regression, of the at least one variable obtained in step a), the blood test not being a Fibrotest, c) obtaining at least one physical data from medical imaging or clinical measurement, from elastometry, or Vibration Controlled Transient Elastography, and d) mathematically combining in a multivariate time-dependent model the variable obtained in step a) and/or the at least one blood test result obtained in step b); and the at least one physical data, obtained in step c) thereby obtaining a prognostic score.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITE D'ANGERS49000 ANGERS
CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERS49100 ANGERS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BERTRAIS, Sandrine THOUARCE, FR 1 3
BOURSIER, Jerome ANGERS, FR 6 15
CALES, Paul AVRILLE, FR 17 56

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