SELENIUM AND SELENIUM-DEPENDENT MOLECULES PREDICT PRESENCE OF MYCOBACTERIA
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Jul 21, 2016
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Jul 21, 2015
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Abstract
Compositions and methods for predicting the presence of a mycobacterial infection in a subject are provided. In some embodiments, the method further comprises assaying the sample to directly detect the presence of the mycobacterial infection if infection is predicted. However, as this is a time-consuming and expensive process, the disclosed methods can be used to predict the presence of the mycobacterium prior to confirmation by direct detection, thereby saving time and money. The disclosed method involves assaying a biological sample from the subject for detection of selenium, wherein the presence of selenium in the sample is an indication of mycobacterium in the sample. Once a mycobacterium is predicated, and optionally confirmed by direct detection, the method can further comprising treating the subject with a therapeutically effective amount of an antibiotic.
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