REDUCING VENTILATOR-INDUCED LUNG INJURY

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United States of America Patent

APP PUB NO 20170021126A1
SERIAL NO

15288495

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods are provided for protecting against ventilation-induced lung injury by promoting equitable liquid distribution in a lung with alveolar flooding, in which flooded and aerated alveoli are interspersed. Since ventilation injuriously over-expands aerated alveoli adjacent to flooded alveoli and a pressure barrier is responsible for trapping liquid in discrete alveoli, the present invention provides various means for overcoming the pressure barrier to, in turn, promote equitable redistribution of flooding liquid amongst alveoli, reduce the number of aerated alveoli located adjacent to flooded alveoli and reduce ventilation injury of the lung. These means of overcoming the pressure barrier include: (i) use of accelerated deflation during mechanical ventilation; and ii) high frequency (>50 Hz) vibration of the lung.

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Patent Owner(s)

Patent OwnerAddress
THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGYCASTLE POINT ON HUDSON HOBOKEN NJ 07030

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Perlman, Carrie E New York, US 6 7

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