Heat Inactivated Poxvirus Improves Vaccination Results
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United States of America Patent
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Jan 26, 2017
app pub date -
Mar 10, 2015
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Mar 10, 2014
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Abstract
Compositions including a heat-inactivated poxvirus, such as vaccinia virus, that induces one or more interferons in a vaccine recipient. The compositions may further include one or more live vaccine vectors and non-replicating vaccine components. Methods of vaccine preparation and administration including a heat-inactivated poxvirus, such as vaccinia virus, improve vaccine immunogenicity and safety.
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