Cyclopropene amino acids and methods
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United States of America Patent
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Sep 15, 2020
Grant Date -
Jan 19, 2017
app pub date -
Mar 10, 2015
filing date -
Mar 14, 2014
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Abstract
The invention relates to a polypeptide comprising an amino acid having a cyclopropene group wherein said cyclopropene group is joined to the amino acid via a carbamate group. Suitably the cyclopropene group is a 1,3-disubstituted cyclopropene such as a 1,3-dimethylcyclopropene. Suitably the cyclopropene group is present as a residue of a lysine amino acid. The invention also relates to methods of making the polypeptides. The invention also relates to an amino acid comprising cyclopropene wherein said cyclopropene group is joined to the amino acid moiety via a carbamate group.
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