Biomarkers and Therapeutic Targets for Sarcoma
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United States of America Patent
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Feb 17, 2015
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Feb 17, 2014
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Abstract
New sarcoma cell surface targets have been identified and include LINGO-1, KCNN1 and CDH23. Specific binding agents that specifically bind to these targets include antibodies and aptamers. Methods of treating sarcoma utilize the specific binding agents. Methods of diagnosing and detecting sarcoma, including metastases and residual disease involve determining the expression of LINGO-1, KCNN1 and CDH23.
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