CRISPR-Mediated Genome Engineering for Protein Depletion
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United States of America Patent
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Jul 6, 2016
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Jul 6, 2015
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Abstract
The present invention provides compositions and methods for tagging a target gene with a degron (e.g., auxin-inducible degron) in a variety of eukaryotic cells using the CRISPR genome-editing technology. Also provided are cells that have been genetically modified using such compositions and methods.
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