COMPOSITIONS FOR INHIBITING DUX4 GENE EXPRESSION AND USES THEREOF

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United States of America Patent

APP PUB NO 20170009230A1
SERIAL NO

15204114

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Abstract

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The present invention is directed to compounds, compositions, and methods useful for modulating DUX4 mRNA or protein expression using gene silencing compounds comprising two or more single stranded antisense oligonucleotides that are linked through their 5′-ends to allow the presence of two or more accessible 3′-ends.

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Patent Owner(s)

Patent OwnerAddress
IDERA PHARMACEUTICALS INC167 SIDNEY STREET CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Agrawal, Sudhir Shrewsbury, US 223 8509
Bhagat, Lakshmi Framingham, US 54 1124
Zhu, Fu-Gang Bedford, US 12 116

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