Activatable antibodies that bind interleukin-6 receptor and methods of use thereof

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United States of America Patent

PATENT NO 10611845
SERIAL NO

15271897

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates generally to activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically binds to interleukin-6 receptor (IL-6R), and to methods of making and using these anti-IL-6R activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.

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Patent Owner(s)

Patent OwnerAddress
CYTOMX THERAPEUTICS INC151 OYSTER POINT BLVD SUITE 400 SOUTH SAN FRANCISCO CA 94080

International Classification(s)

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  • 2016 Application Filing Year
  • A61K Class
  • 19101 Applications Filed
  • 13019 Patents Issued To-Date
  • 68.16 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances20162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Flandez, Jeanne Grace Oakland, US 10 83
Hostetter, Daniel Robert Rocklin, US 25 387
Moore, Stephen James Danville, US 32 431
Nguyen, Margaret Thy Luu San Francisco, US 17 177
Sagert, Jason Gary San Mateo, US 41 799
Vasiljeva, Olga Cupertino, US 46 512
West, James William Bend, US 43 805

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges13636645326377163101 - 1011 - 2021 - 3031 - 4041 - 5051 - 600100020003000400050006000700080009000100001100012000130001400015000

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