Activatable antibodies that bind interleukin-6 receptor and methods of use thereof

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United States of America Patent

PATENT NO 10611845
SERIAL NO

15271897

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Abstract

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The invention relates generally to activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically binds to interleukin-6 receptor (IL-6R), and to methods of making and using these anti-IL-6R activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications.

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Patent Owner(s)

Patent OwnerAddress
CYTOMX THERAPEUTICS INC151 OYSTER POINT BOULEVARD SUITE 400 SOUTH SAN FRANCISCO CA 94080

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Flandez, Jeanne Grace Oakland, US 10 83
Hostetter, Daniel Robert Rocklin, US 25 387
Moore, Stephen James Danville, US 32 431
Nguyen, Margaret Thy Luu San Francisco, US 17 177
Sagert, Jason Gary San Mateo, US 41 799
Vasiljeva, Olga Cupertino, US 46 512
West, James William Bend, US 43 805

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