COMBINATION TREATMENT FOR MULTIPLE SCLEROSIS
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United States of America Patent
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Issued Date -
Jan 5, 2017
app pub date -
Mar 12, 2015
filing date -
Mar 13, 2014
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Abstract
The present application provides evidence that a combined blockade against alpha-4 integrin and MCAM is more effective than against either molecule alone. In consequence, the invention provides methods of combination treatment in which both an antagonist of alpha-4 integrin and an MCAM antagonist are administered to a subject having or at risk of multiple sclerosis or other autoimmune disease.
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