USE OF A NEUROFILAMENT PEPTIDE FOR THE TREATMENT OF GLIOMA
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United States of America Patent
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Jan 5, 2017
app pub date -
Aug 5, 2016
filing date -
Dec 14, 2009
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Abstract
The present invention provides a new drug to treat malignant glioma, which is the most prevalent type of primary tumor of the central nervous system (CNS). The present invention indeed shows that the isolated NFL-TBS40-63 peptide is highly specific for glioma cells, in which it triggers apoptosis. It is therefore presented here for use in a method for treating malignant glioma. The present invention further relates to the use of the NFL-TBS40-63 peptide for detecting specifically glioma cells either in vivo, or in vitro, or for addressing chemical compounds to said tumor cells.
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