METHODS AND KITS FOR PREDICTING INFUSION REACTION RISK AND ANTIBODY-MEDIATED LOSS OF RESPONSE BY MONITORING SERUM URIC ACID DURING PEGYLATED URICASE THERAPY

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United States of America Patent

SERIAL NO

15165318

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Abstract

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Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response during intravenous PEGylated uricase therapy in gout patients is provided. Routine SUA monitoring can be used to identify patients receiving PEGylated uricase who may no longer benefit from treatment and who are at greater risk for infusion reactions.

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Patent Owner(s)

Patent OwnerAddress
HORIZON THERAPEUTICS USA INC1 HORIZON WAY DEERFIELD IL 60015

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Rosario-Jansen, Theresa Randolph, US 13 223
Wright, David Erick Romona, US 8 98

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