COMBINATION THERAPY COMPRISING AN INHIBITOR OF JAK, CDK, AND PIM

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United States of America Patent

APP PUB NO 20160375024A1
SERIAL NO

15039869

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Abstract

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The present invention relates to a pharmaceutical combination which comprises (a) a JAK inhibitor compound, (b) a CDK inhibitor, and (c) a PIM kinase inhibitor compound, and optionally, at least one pharmaceutically acceptable carrier for simultaneous, separate or sequential use, in particular for the treatment of a myeloid neoplasm or leukemia; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of myeloid neoplasm or leukemia; a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use; and to a method of treatment of a mammal, especially a human.

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NOVARTIS AGLICHTSTRASSE 35 BASEL 4056

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  • 2014 Application Filing Year
  • A61K Class
  • 14144 Applications Filed
  • 11600 Patents Issued To-Date
  • 82.02 % Issued To-Date
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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CAO, Zhu Alexander Acton, US 17 232
PINZON-ORTIZ, Maria Upton, US 3 0
RONG, Xianhui Boxborough, US 5 155

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