DRUG-ELUTING COATINGS ON POLY(DL-LACTIDE)-BASED SCAFFOLDS
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United States of America Patent
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Issued Date -
Dec 29, 2016
app pub date -
Jun 29, 2015
filing date -
Jun 29, 2015
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Abstract
Stents including a poly(D,L-lactide)(PDLLA)-based scaffold and PDLLA based therapeutic layer are disclosed. The PDLLA based scaffold may be amorphous and may include a primer layer. Methods of applying the PDLLA-based coating to the scaffold are disclosed with solvent processing methods using a solvent blend are also disclosed. Methods of removing residual solvent from a PDLLA-base coating that also condition the scaffold are disclosed. Methods of treating restenosis that release drugs to prevent restenosis without interfering with the natural positive remodeling of a vessel are disclosed.
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