ENHANCING THE IN-VIVO EFFICIENCY OF PARTICLE DELIVERY THROUGH NON-COVALENT INTERACTION WITH RED BLOOD CELL SURFACE PROTEINS
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United States of America Patent
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Dec 22, 2016
app pub date -
Jun 18, 2015
filing date -
Jun 18, 2015
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Abstract
The present invention relates to the production of modified microscale and nanoscale particles that have enhanced in vivo delivery characteristics. The resultant particles can be used in any of a number of applications including informatics, detection, diagnosis, imaging, and/or therapeutics. Further, the modified particles of the present invention have enhanced circulation half time and elimination rate constant characteristics, and enhanced biodistribution.
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