REDUCTION OF TRAF1 LEVELS COMBINED WITH NUTRIENT STRESS FOR TREATING LYMPHOCYTE-RELATED CANCERS

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United States of America Patent

APP PUB NO 20160361391A1
SERIAL NO

15121563

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Abstract

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The present disclosure provides methods and uses for treating lymphocyte related cancers comprising administering a nutrient stress-inducing agent in combination with an agent that lowers the levels of or inhibits TRAF1. Also provided are methods of determining treatment for a subject with a lymphocyte related cancer and assays for identifying a PKN1 inhibitor.

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Patent Owner(s)

Patent OwnerAddress
THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO108 COLLEGE ST 5TH FLOOR SUITE W540 TORONTO M5G 0C6

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abdul, Sater Ali Toronto, CA 1 0
Laister, Rob Toronto, CA 1 0
McPherson, Ann Josephine Toronto, CA 1 0
Minden, Mark Toronto, CA 3 2
Watts, Tania Helen Toronto, CA 1 0

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