Light-Up Probes Based On Fluorogens With Aggregation Induced Emission Characteristics For Cellular Imaging And Drug Screening

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United States of America Patent

SERIAL NO

15114692

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention is drawn toward luminogens and chemical compositions comprising a target recognition motif, a hydrophilic moiety, a linking moiety, and at least one luminogen. Additionally presented are methods of: assessing the conversion of a prodrug into its active form, assessing the therapeutic efficacy of a prodrug, detecting glutathione in a biological sample, detecting alkaline phosphatase in a sample, and conducting fluorescence imaging or magnetic resonance imaging with the use of luminogen-containing compositions.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL UNIVERSITY OF SINGAPORE21 LOWER KENT RIDGE ROAD SINGAPORE 119077 SINGAPORE
THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGYCLEAR WATER BAY KOWLOON

International Classification(s)

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  • 2015 Application Filing Year
  • A61K Class
  • 16157 Applications Filed
  • 11882 Patents Issued To-Date
  • 73.55 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Yilong Kowloon, HK 68 167
Kwok, Tsz Kin Kowloon, HK 8 19
Liang, Jing Singapore, SG 186 752
Liu, Bin Singapore, SG 1027 7414
Shao, Jinjun Singapore, SG 2 3
Song, Zhegang Kowloon, HK 1 2
Tang, Benzhong Kowloon, HK 58 114
Yuan, Youyong Singapore, SG 3 6

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Patent Citation Ranking

  • 2 Citation Count
  • A61K Class
  • 38.16 % this patent is cited more than
  • 9 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges6209860894426710349291291182201 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0500100015002000250030003500400045005000550060006500700075008000850090009500

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