Reduction of bias in genomic coverage measurements
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United States of America Patent
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Nov 24, 2020
Grant Date -
Dec 8, 2016
app pub date -
Feb 24, 2015
filing date -
Feb 20, 2013
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Abstract
Methods are provided for detecting and quantitating molecules using fluidics. In some embodiments, the methods comprise minimizing or eliminating biases caused by label density, or minimizing or eliminated biases caused by factors other than label density. In some embodiments, the methods comprise automated identification of genetic structural variation. In some embodiments, the methods comprise analyzing blood to detect the presence of circulating DNA or cells from a fetus or tumor.
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