BIOMARKERS FOR CARDIOVASCULAR DISEASE
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United States of America Patent
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Issued Date -
Dec 1, 2016
app pub date -
Feb 13, 2015
filing date -
Feb 14, 2014
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Abstract
Described herein are methods for diagnosing or assessing and treating an individual for cardiovascular disease based on the individual's normalized level of biomarkers. For example, a level of Lp-PLA2 mass or Lp-PLA2 activity normalized to a level of Lp-PLA2 total mass (e.g. total mass) may be used. Described herein are new and more accurate diagnostic indicators to help identify and stratify individuals having cardiovascular disease or at risk for cardiovascular disease, as well as methods for treating such patients. The methods and techniques described herein may be especially useful for detecting early stages of cardiovascular disease, and may be particularly useful for distinguishing a person having cardiovascular disease from a person without cardiovascular disease.
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