Assisted particle size reduction process

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United States of America Patent

PATENT NO 10328027
APP PUB NO 20160346206A1
SERIAL NO

15115193

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A new scalable process to control the particle size and the particle size distribution, comprising 5 steps: (i) suspension preparation in a mixture of solvents in which the API and/or excipient is partially soluble in one of the solvents; (ii) particle size reduction of the suspension; (iii) aging; (iv) stopping the aging by solvent removal; and (v) optionally, a step of isolating the processed ingredients in the form of powder.

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Patent Owner(s)

Patent OwnerAddress
HOVIONE INTERNATIONAL LTDHONG KONG

International Classification(s)

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  • 2015 Application Filing Year
  • A61K Class
  • 16157 Applications Filed
  • 11882 Patents Issued To-Date
  • 73.55 % Issued To-Date

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cacela, Constanca Lisbon, PT 4 13
Costa, Eunice Santa Iris da Azoia, PT 4 1
Sobral, Luis Loures, PT 13 10
Temtem, Marcio Quinta do Conde, PT 8 26
Villax, Peter Lisbon, PT 11 422

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Patent Citation Ranking

  • 1 Citation Count
  • A61K Class
  • 58.87 % this patent is cited more than
  • 6 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges11535744839711494311101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6081 - 9091 - 1000500100015002000250030003500400045005000550060006500700075008000850090009500100001050011000115001200012500

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