Methods and compositions for producing a cell expressing a T cell receptor

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United States of America Patent

PATENT NO 10654907
APP PUB NO 20160340403A1
SERIAL NO

15111639

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Abstract

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Provided is a method for determining a TCR polypeptide chain that can form a TCR specific for a peptide of interest. Also provided are methods and compositions for producing a cell expressing a T cell receptor (TCR) specific for a peptide of interest, methods and compositions for producing a TCR chain nucleic acid and/or pair of TCR chain polypeptides and/or nucleic acids encoding a TCR, a cell population comprising the cell harboring the nucleic acids encoding a TCR obtained by said method, and a method for treating a disorder comprising administering to the subject said cell population.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY HEALTH NETWORK190 ELIZABETH STREET R FRASER ELLIOTT BUILDING - ROOM 1S-417 TORONTO M5G 2C4

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hirano, Naoto Toronto, CA 44 210
Nakatsugawa, Munehide Sapporo, JP 5 2
Ochi, Toshiki Toon, JP 3 3

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges3699137088251501 - 1011 - 2021 - 3031 - 4041 - 5001000200030004000250500750125015001750225025002750325035003750

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