TRIAZOLOPYRIDINE JAK INHIBITOR COMPOUNDS AND METHODS

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United States of America Patent

APP PUB NO 20160333011A1
SERIAL NO

15220087

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A compound of Formula I, enantiomers, diastereomers, tautomers or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are defined herein, are useful as JAK kinase inhibitors. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of JAK kinase activity in a patient are disclosed.

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Patent Owner(s)

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GENENTECH INCCALIFORNIA USA CALIFORNIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Haiying, He Shanghai, CN 8 24
Hurley, Christopher Hertfordshire, GB 31 246
Jifu, Zheng Shanghai, CN 8 24
Junping, Zhao Yanan, CN 8 24
Liang, Jun Palo Alto, US 203 1123
Liu, Wendy Foster City, US 23 115
Lyssikatos, Joseph P Peidmont, US 160 1669
Magnuson, Steven R Dublin, US 42 319
Pastor, Richard San Francisco, US 35 177
Siu, Michael Burlingame, US 53 265
Xing, Xu Chengdu, CN 9 24
Yisong, Xiao Shanghai, CN 8 24
Zhu, Bing-Yan Palo Alto, US 107 2017

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