NOVEL 2-PHENYLBENZOFURAN DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PRODUCTION METHOD FOR SAME AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASE COMPRISING SAME AS ACTIVE INGREDIENT

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United States of America Patent

SERIAL NO

15221025

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Abstract

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The present invention relates to a novel 2-phenylbenzofuran derivative or a pharmaceutically acceptable salt thereof, a production method for the same, and a pharmaceutical composition for preventing or treating an inflammatory disease comprising the same as an active ingredient, and the novel 2-phenylbenzofuran derivative or the pharmaceutically acceptable salt thereof according to the present invention is outstandingly effective in suppressing NO, IL-6, and TNF-alpha induced by macrophages, and therefore can advantageously be used in a pharmaceutical composition for preventing or treating an inflammatory disease.

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Patent Owner(s)

Patent OwnerAddress
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY125 GWAHAK-RO YUSEONG-GU DAEJEON 34141 34141
DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATIONSEOUL 04620

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
AHN, Kyung Seop Daejeon, KR 40 24
KIM, Doo-Young Daejeon, KR 40 133
KIM, Jung Hee Daejeon, KR 35 152
KWON, Ok-Kyoung Daejeon, KR 20 1
LEE, Kyeong Seoul, KR 35 667
OH, Sei-Ryang Daejeon, KR 26 10
RYU, Hyung Won Daejeon, KR 18 1
XU, Xuezhen Goyang-si, KR 10 1

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