GENERATION OF LAYERED TRANSCRIPTIONAL CIRCUITRY USING CRISPR SYSTEMS
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United States of America Patent
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Issued Date -
Nov 10, 2016
app pub date -
May 4, 2016
filing date -
May 4, 2015
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Abstract
Provided herein, in some embodiments, are modular transcriptional architectures and methods for regulated expression of guide RNAs in cells, such as human cells, which are based on Clustered Regularly Interspaced Palindromic Repeats (CRISPR) systems.
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