COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

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United States of America Patent

SERIAL NO

15144921

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Abstract

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The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors.

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Patent Owner(s)

Patent OwnerAddress
VERTEX PHARMACEUTICALS INCORPORATED50 NORTHERN AVENUE BOSTON MA 02210

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alphonsus, Knegtel Ronald Marcellus Abingdon, GB 4 187
Boyall, Dean Faringdon, GB 36 1031
Charrier, Jean-Damien Grove, GB 174 6159
Davis, Christopher John Salisbury, GB 20 315
Durrant, Steven John Abingdon, GB 37 1623
Etxebarria, I Jardi Gorka Abingdon, GB 24 447
Fraysse, Damien Abingdon, GB 67 1611
Kay, David Purton, GB 135 5214
Pinder, Joanne Didcot, GB 55 2240

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