LIVER X RECEPTOR AGONISTS AND USES THEREOF

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United States of America Patent

APP PUB NO 20160324981A1
SERIAL NO

15147863

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein are antibody drug conjugates having an antibody or antibody fragment that binds a cell surface molecule on a target cell, wherein the target cell is a lymphocyte and a therapeutic agent that has a therapeutic effect in a subject in need thereof. Further disclosed herein are antibody drug conjugates having an antibody or antibody fragment that binds a cell surface molecule on a target cell; and a therapeutic agent that binds an intracellular moiety of the target cell. These antibody drug conjugates may be used for treating cardiovascular diseases.

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Patent Owner(s)

Patent OwnerAddress
THE SCRIPPS RESEARCH INSTITUTE10550 NORTH TORREY PINES ROAD MAIL DROP TPC-8 LA JOLLA CA 92037

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHATTERJEE, Arnab K San Diego, US 45 188
CHENG, Bo San Diego, US 120 214
LIM, Reyna K V San Diego, US 1 5
PINKERTON, Stephanie San Diego, US 3 45
SCHULTZ, Peter G La Jolla, US 236 4625
TREMBLAY, Matthew S San Diego, US 7 8
YU, Shan San Diego, US 32 221

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