Artificial match-type miRNA for controlling gene expression and use therefor
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United States of America Patent
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Mar 2, 2021
Grant Date -
Nov 3, 2016
app pub date -
Dec 27, 2014
filing date -
Dec 27, 2013
priority date (Note) -
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status (Latency Note)
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Abstract
The invention provides an artificial match-type miRNA utilizing miRNA. In particular, the invention provides a single strand nucleic acid containing an X region and a Y region, wherein the 3′-terminal of the X region and the 5′-terminal of the Y region are linked via a linker region of a non-nucleotide structure, the X region contains a guide strand sequence of a mature miRNA, and the Y region contains a sequence completely complementary to the X region is an artificial match-type miRNA. The artificial match-type miRNA can suppress expression of the target gene.
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International Classification(s)
- 2014 Application Filing Year
- A61K Class
- 14144 Applications Filed
- 11600 Patents Issued To-Date
- 82.02 % Issued To-Date
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- 0 Citation Count
- A61K Class
- 0 % this patent is cited more than
- 4 Age
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