METHODS FOR TREATING FATTY LIVER DISEASE

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United States of America Patent

APP PUB NO 20160318983A1
SERIAL NO

15148162

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Abstract

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In certain aspects, the present invention provides compositions and methods for treating fatty liver disease by administering an antagonist of an ActRIIB signaling pathway. Examples of such antagonists include ActRIIB polypeptides, anti-ActRIIB antibodies, anti-myostatin antibodies, anti-GDF3 antibodies and anti-activin A or B antibodies. A variety of hepatic and metabolic disorders may be improved by treating fatty liver disease.

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Patent Owner(s)

Patent OwnerAddress
ACCELERON PHARMA INC128 SIDNEY STREET CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Koncarevic, Alan Chicago, US 7 299
Lachey, Jennifer Arlington, US 34 427
Seehra, Jasbir Lexington, US 147 4048
Sherman, Matthew L Newton, US 44 1414

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