Combined agent for cell therapy of corneal endothelial cell
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United States of America Patent
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Mar 30, 2021
Grant Date -
Nov 3, 2016
app pub date -
Dec 27, 2013
filing date -
Dec 27, 2013
priority date (Note) -
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Abstract
The present invention provides an agent for treating or preventing a disease, a disorder or a condition of a corneal endothelium, said agent comprising a corneal endothelial cell and a myosin II-specific inhibitor. More specifically, the myosin II-specific inhibitor is blebbistatin. The disease, the disorder or the condition is typically a disorder associated with Fuchs endothelial corneal dystrophy or corneal endothelial dysfunction (bullous keratopathy). Also provided is a method for treating or preventing a corneal endothelial disease, said method comprising a step of administering an effective amount of a myosin II-specific inhibitor together with a corneal endothelial cell to a subject.
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