METHODS OF TREATING OR PREVENTING BRAIN DAMAGE DUE TO HYPOXIC-ISCHEMIA

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United States of America Patent

APP PUB NO 20160317473A1
SERIAL NO

14716007

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Abstract

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This disclosure relates to managing brain injury. In certain embodiments, this disclosure relates to methods comprising administering an effective amount of an inhibitor of sphingosine-1-phoshate signaling, an inhibitor of retinoic-acid-receptor-related orphan receptors α or γ, and/or an inhibitor of tPA microglial activation to a subject in need thereof. Typically, the subject is a neonate or a neonate born prematurely.

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Patent Owner(s)

Patent OwnerAddress
EMORY UNIVERSITY1599 CLIFTON ROAD NE 4TH FLORR ATLANTA GA 30322
CHILDREN'S HEALTHCARE OF ATLANTA INC1575 NORTHEAST EXPRESSWAY ATLANTA GA 30329

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kuan, Chia-Yi Marietta, US 4 13
Sun, Yu-Yo Decatur, US 1 0
Yang, Dianer Lutherville-Timonium, US 1 0

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