USE OF NUCLEIC ACID AGENTS FOR ULTRA-SENSITIVE DIGITAL DETECTION AND QUANTIFICATION OF TARGET MOLECULES
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Oct 27, 2016
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Jan 14, 2015
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Jan 14, 2014
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Described herein are methods and systems for detecting and quantifying target molecules and particles in a sample using a plurality of capture objects and a plurality of detection objects. The methods and system utilize nucleic-acid aptamers and digital DNA amplification and detection technology to transform the analog signals obtained from conventional ELISA to digital signals from single molecule counting.
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