COMPOUNDS FOR TREATMENT OF CARDIAC ARRHYTHMIAS
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United States of America Patent
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Oct 27, 2016
app pub date -
Dec 5, 2014
filing date -
Dec 5, 2013
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Abstract
Compounds and methods thereof for reducing cardiac arrhythmia are described. In particular, compounds generated by adding chemical groups that enhance the electron donor properties of RyR inhibitors may increase inhibitor potency and thus allow for new more potent anti-arrhythmic drugs. One advantage of the compounds and methods described is a potential for drugs with enhanced electron donor properties that may be used at lower concentrations and exhibit less non-specific effects.
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