CANCER TREATMENTS USING COMBINATIONS OF MEK TYPE 1 AND ERK INHIBITORS
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United States of America Patent
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Issued Date -
Oct 27, 2016
app pub date -
Dec 19, 2014
filing date -
Dec 20, 2013
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Abstract
The present invention provides, inter alia, methods, kits, and pharmaceutical compositions for treating or ameliorating the effects of a cancer in a subject in need thereof. The method comprises administering to the subject an effective amount of (i) a first anti-cancer agent, which is BVD-523 or a pharmaceutically acceptable salt thereof and (ii) a second anti-cancer agent, which is a type 1 MEK inhibitor or a pharmaceutically acceptable salt thereof, to treat or ameliorate the effects of the cancer. Additional methods for effecting cancer cell death are also provided.
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