METHOD FOR DETECTING PREDISPOSITION FOR HEPATITIS B TO BECOME CHRONIC
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United States of America Patent
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Oct 20, 2016
app pub date -
Aug 28, 2014
filing date -
Aug 30, 2013
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Abstract
An object of the present invention is to provide a method for detecting predisposition for chronicity of hepatitis B and/or the pathological progress, including an allele associated with chronicity of hepatitis B and/or the pathological progress. The above-described object is achieved by providing a method that includes a process of identifying alleles which are susceptible and resistant to chronicity of hepatitis B and/or the pathological progress in which a difference between a chronic hepatitis B patient group and a healthy control group is accurately reflected and comparing the alleles with base sequences or amino acid sequences corresponding to the alleles in a specimen; a process of analyzing whether bases of sites corresponding to the alleles in the base sequences of the specimen match bases of the alleles; and a process of specifying whether the hepatitis B of the specimen becomes chronic and/or the pathology is progressed, a method of performing inspection using the method, a reagent used for the method, and a test kit including the reagent.
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