Process for the preparation of 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide and intermediates thereof

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United States of America Patent

PATENT NO 10329254
APP PUB NO 20160304455A1
SERIAL NO

15134028

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Abstract

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The invention relates to a novel process for the preparation of rac-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide (I) in pharmaceutically acceptable polymorphic form, through the conversion of a 3-bromo-2-oxo-cyclohexanecarboxylic acid alkyl ester into 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid alkyl ester, which in turn is processed to yield the final product.

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AOP ORPHAN IP AGSTADTLE 28 VADUZ FL-9490

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Diodato, Enrica Siena, IT 2 0
Marcucci, Katia Siena, IT 2 0
Rettig, Martin Schwanau-nonnenweier, DE 3 1
Roberts, Huw Flint Wales, GB 2 0
Thomas, Russell Siena, IT 15 55
Wiedenau, Paul Siena, IT 2 0

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