Therapeutic drug for diseases related to endoplasmic reticulum cell death in corneal endothelium

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United States of America Patent

PATENT NO 11382904
APP PUB NO 20160296505A1
SERIAL NO

15031183

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Abstract

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The present invention provides a treatment drug or prophylactic drug for diseases, disorders, or conditions related to endoplasmic reticulum (ER) stress. Specifically, the present invention provides a treatment drug or prophylactic drug for diseases, disorders, or conditions related to endoplasmic reticulum (ER) stress in the corneal epithelium, the drug containing a TGFβ-signal inhibitor. As a preferred TGFβ-signal inhibitor, the drug contains 4-[4-(1,3-benzodioxole-5-yl)-5-(2-pyridinyl)-1H-imidazole-2-yl]benzamide.

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Patent Owner(s)

Patent OwnerAddress
THE DOSHISHA601 GEMBU-CHO KARASUMA-HIGASHI-IRU IMADEGAWA-DORI KAMIGYO-KU KYOTO-SHI KYOTO 602-8580
SENJU PHARMACEUTICAL CO LTDOSAKA JAPAN OSAKA
KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION465 KAJII-CHO KAWARAMACHI-DORI HIROKOJI-AGARU KAMIGYO-KU KYOTO-SHI KYOTO 602-8566

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kinoshita, Shigeru Kyoto, JP 95 409
Koizumi, Noriko Kyotanabe, JP 38 65
Okumura, Naoki Kyotanabe, JP 39 55

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