EBNA1 inhibitors and their method of use

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United States of America Patent

PATENT NO 9856214
SERIAL NO

15036211

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides EBNA1 inhibitors, and pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by EBNA1 activity such as, but not limited to, cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and/or rheumatoid arthritis. The compounds and compositions of the invention are further useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection. The compounds and compositions of the invention are further useful for the treatment of diseases caused by lytic EBV infection.

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Patent Owner(s)

  • THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lieberman, Paul M Wynnewood, US 14 18
McDonnell, Mark E Lansdale, US 23 44
Messick, Troy E Upper Darby, US 10 10
Reitz, Allen B Lansdale, US 136 797
Smith, Garry R Royersford, US 22 144
Velvadapu, Venkata Ankeny, US 21 12
Zhang, Yan Fort Washington, US 881 7426

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