Compositions and Methods for Treating Alzheimer's Disease

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20160280742A1
SERIAL NO

15056546

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure provides for a hyperimmune preparation comprising human polyclonal antibodies or fragments thereof specific to a cyclic peptide having an amino acid sequence comprising SNK. The cyclic peptide may comprise an amino acid sequence GSNK (SEQ ID NO: 1), SNKG (SEQ ID NO: 2), GSNKG (SEQ ID NO: 3), CSNKG (SEQ ID NO: 4), CGSNKGC (SEQ ID NO: 5), CGSNKGG (SEQ ID NO: 6), or CCGSNKGC (SEQ ID NO: 7). The antibodies in the hyperimmune preparation may have a titer ranging from about 200 to about 400 mean fluorescence intensity (MFI). In one embodiment, greater than about 80% of the antibodies in the hyperimmune preparation are IgG. The fragments of the antibodies are Fab, F(ab′)2, scFv, disulfide linked Fv, or mixtures thereof.

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Patent Owner(s)

Patent OwnerAddress
CANGENE CORPORATIONWINNIPEG MANITOBA R3T 5Y3

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cashman, Neil R Vancouver, CA 44 292
McClarty, Grant Winnipeg, CA 3 3

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