INTERLEUKIN-1 (IL-1) INHIBITORS FOR TREATING FERTILITY DISORDERS

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United States of America Patent

SERIAL NO

15032835

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Abstract

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The invention provides IL-1 inhibitors, methods and uses thereof for retaining ovarian follicle reserve in a mammalian subject, treating infertility and improving responsiveness and sensitivity to COH. The invention further provides methods for improving oocyte quality and/or survival, specifically for IVF, and kits for combining COH treatment with the sensitizing IL-inhibitors of the invention.

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Patent Owner(s)

Patent OwnerAddress
RAMOT AT TEL-AVIV UNIVERSITY LTDP O BOX 39296 TEL AVIV 6139201
TEL HASHOMER MEDICAL RESEARCH INFRASTRUCTURE AND SERVICES LTDSHEBA MEDICAL CENTER TEL HASHOMER 5262000

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HARATS, Dror Ramat Gan, IL 50 843
KAMARI, Yehuda Tel Aviv, IL 2 1
SHAISH, Aviv Talmei Yehyel, IL 11 23
SHALGI, Ruth Herzliya, IL 5 15
URI, Shiri Hod Hasharon, IL 1 1

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