SENESCENCE AND SENESCENCE ASSOCIATED SECRETORY PHENOTYPE
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United States of America Patent
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Sep 29, 2016
app pub date -
Nov 14, 2014
filing date -
Nov 14, 2013
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The present invention relates to a method of treating or preventing DNA damage in a cell or cellular senescence of a cell or induction of the senescence associated secretory phenotype (SASP) in a cell, or for treating or preventing the effects of aging, or for preventing or treating cellular senescence and/or induction of SASP associated with high caloric intake or obesity, or for reducing the side effects of chemotherapy, radiotherapy, corticoid treatment, anti-retroviral treatment, or PPARγ agonist treatment, comprising administering an effective amount of an NAD+ agonist.
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