BIOMARKER OF LIVER CANCER AND USES THEREOF

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United States of America Patent

APP PUB NO 20160274118A1
SERIAL NO

14812269

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to uses of nucleolin as a biomarker of liver cancer, comprising predicting, detecting, diagnosing or monitoring liver cancer, high risk of liver cancer, or high risk of vascular invasion of hepatoma cells in a subject, and assessing prognosis of a subject suffered from liver cancer by nucleolin expression level. The biomarkers for determining expression level of nucleolin, kit for determining liver cancer, high risk of liver cancer, or high risk of vascular invasion of hepatoma cells in a subject by expression level of nucleolin, and use of small interfering RNA or antibody specific for recognizing nucleolin in manufacturing medicine for treating liver cancer are also included in the present invention.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL SUN YAT-SEN UNIVERSITYNO 70 LIENHAI RD KAOHSIUNG 80424

International Classification(s)

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  • 2015 Application Filing Year
  • G01N Class
  • 11310 Applications Filed
  • 8345 Patents Issued To-Date
  • 73.79 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, San-Cher Kaohsiung, TW 2 0
Hu, Tsung-Hui Kaohsiung, TW 1 0
Kung, Mei-Lang Kaohsiung, TW 1 0
Tai, Ming-Hong Kaohsiung, TW 7 1

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges232940745921838355241515882101 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +0250500750100012501500175020002250250027503000325035003750400042504500

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