DIAGNOSTIC METHODS FOR PAR4 ANTAGONIST THERAPY

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United States of America Patent

APP PUB NO 20160274108A1
SERIAL NO

15031941

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The disclosure provides methods for identifying a PAR4 agonist responder or a PAR4 antagonist responder comprising contacting a PAR4 agonist with platelets in a sample obtained from a subject in need thereof. The methods also include administering a PAR4 antagonist to the subject identified as a PAR4 agonist responder or a PAR4 antagonist responder. The invention also includes methods of treating the subjects and a pharmaceutical kit comprising a PAR4 agonist.

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Patent Owner(s)

Patent OwnerAddress
BRISTOL-MYERS SQUIBB COMPANYROUTE 206 & PROVINCE LINE ROAD PRINCETON NJ 08543

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
OUWEHAND, Willem H Cambridge, GB 1 1
YANG, Jing Princeton, US 317 1325

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