METHODS OF REDUCING CORNEAL ENDOTHELIAL CELL LOSS

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United States of America Patent

APP PUB NO 20160271224A1
SERIAL NO

15037292

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided herein are methods of reducing corneal endothelial cell loss (e.g., nerve loss-related corneal endothelial cell loss) that include selecting a subject identified as having an eye with reduced numbers of corneal nerves as compared to a reference eye, e.g., an eye of a healthy control, and administering vasoactive intestinal peptide (VIP) or a nucleic acid encoding VIP to the selected subject.

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Patent Owner(s)

Patent OwnerAddress
MASSACHUSETTS EYE & EAR INFIRMARY243 CHARLES STREET BOSTON MA 02114

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hamrah, Pedram Wellesley, US 26 109
Jurkunas, Ula Winchester, US 4 0
Yamaguchi, Takefumi Tokyo, JP 3 0

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