COMPOSITIONS AND METHODS FOR CARDIOVASCULAR DISEASE

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United States of America Patent

SERIAL NO

15070774

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides small molecule inhibitors of BMP signaling. These compounds may be used to reduce circulating levels of ApoB-100 or LDL. These compounds may also be used to treat or prevent acquired or congenital hypercholesterolemia or hyperlipoproteinemia; diseases, disorders, or syndromes associated with defects in lipid absorption or metabolism; or diseases, disorders, or syndromes caused by hyperlipidemia.

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Patent Owner(s)

Patent OwnerAddress
THE GENERAL HOSPITAL CORPORATION55 FRUIT STREET BOSTON MA 02114

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bloch, Kenneth D Chestnut Hill, US 22 277
Derwall, Matthias Moers, DE 2 14
Malhotra, Rajeev Boston, US 14 162
Yu, Paul B Boston, US 24 128

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