DEGRADABLE ADAPTORS FOR BACKGROUND REDUCTION
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United States of America Patent
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Sep 8, 2016
app pub date -
Nov 18, 2014
filing date -
Nov 18, 2013
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The present disclosure provides systems, processes, articles of manufacture, and compositions that relate to the use of degradable adaptors for background reduction in various nucleic acid manipulations. In particular, adaptors are provided that can be degraded to an extent that the degradation products are incapable or are substantially incapable from participating in subsequent reactions, such as ligation, primer extension, amplification, and sequencing reactions.
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