Processes for preparing pyrazolyl-substituted pyrrolo[2,3-d]pyrimidines

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United States of America Patent

PATENT NO 9908888
SERIAL NO

15016918

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Abstract

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The present invention is related to processes for preparing chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines of Formula III, and related synthetic intermediate compounds. The chiral substituted pyrazolyl pyrrolo[2,3-d]pyrimidines are useful as inhibitors of the Janus Kinase family of protein tyrosine kinases (JAKs) for treatment of inflammatory diseases, myeloproliferative disorders, and other diseases.

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Patent Owner(s)

Patent OwnerAddress
INCYTE HOLDINGS CORPORATION1801 AUGUSTINE CUT-OFF WILMINGTON DE 19803
INCYTE CORPORATION1801 AUGUSTINE CUT-OFF WILMINGTON DE 19803

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Li, Mei Newark, US 177 2134
Lin, Qiyan Newark, US 24 432
Liu, Pingli Newark, US 70 1664
Meloni, David Bear, US 19 710
Metcalf, Brian W Moraga, US 109 2484
Pan, Yongchun Newark, US 54 942
Rodgers, James D Landenberg, US 106 8792
Wang, Haisheng Hockessin, US 694 7057
Xia, Michael Wilmington, US 39 1033
Yue, Tai-Yuen Hockessin, US 17 488
Zhou, Jiacheng Newark, US 121 2378

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